KISSPEPTIN

Kisspeptin-10 acts through the GPR54 receptor (also known as the KISS1R receptor) in the hypothalamus to trigger the release of gonadotropin-releasing hormone (GnRH). This upstream signal initiates a cascade involving luteinizing hormone (LH) and follicle-stimulating hormone (FSH), which are central to reproductive hormone balance. Its role as a master regulator of the HPG axis has made it a key focus in research related to fertility, hormonal disorders, and delayed or precocious puberty